STOM, stomatin, 2040

N. diseases: 39; N. variants: 1
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.010 AlteredExpression disease BEFREE Stomatin-like protein-2 (SLP-2) gene belongs to the stomatin supergene family, and previous studies have revealed up-regulated SLP-2 expression in gallbladder cancer, lung cancer, and esophageal cancer, while the role of SLP-2 in colorectal cancer (CRC) remains unclear and needs further investigation. 30389319 2019
CUI: C0153452
Disease: Malignant neoplasm of gallbladder
Malignant neoplasm of gallbladder
0.010 AlteredExpression disease BEFREE Stomatin-like protein-2 (SLP-2) gene belongs to the stomatin supergene family, and previous studies have revealed up-regulated SLP-2 expression in gallbladder cancer, lung cancer, and esophageal cancer, while the role of SLP-2 in colorectal cancer (CRC) remains unclear and needs further investigation. 30389319 2019
CUI: C0235782
Disease: Gallbladder Carcinoma
Gallbladder Carcinoma
0.010 AlteredExpression disease BEFREE Stomatin-like protein-2 (SLP-2) gene belongs to the stomatin supergene family, and previous studies have revealed up-regulated SLP-2 expression in gallbladder cancer, lung cancer, and esophageal cancer, while the role of SLP-2 in colorectal cancer (CRC) remains unclear and needs further investigation. 30389319 2019
CUI: C4525297
Disease: Stage 0 Gallbladder Cancer AJCC v8
Stage 0 Gallbladder Cancer AJCC v8
0.010 AlteredExpression disease BEFREE Stomatin-like protein-2 (SLP-2) gene belongs to the stomatin supergene family, and previous studies have revealed up-regulated SLP-2 expression in gallbladder cancer, lung cancer, and esophageal cancer, while the role of SLP-2 in colorectal cancer (CRC) remains unclear and needs further investigation. 30389319 2019
Stage IIA Gallbladder Cancer AJCC v8
0.010 AlteredExpression disease BEFREE Stomatin-like protein-2 (SLP-2) gene belongs to the stomatin supergene family, and previous studies have revealed up-regulated SLP-2 expression in gallbladder cancer, lung cancer, and esophageal cancer, while the role of SLP-2 in colorectal cancer (CRC) remains unclear and needs further investigation. 30389319 2019
Stage IIB Gallbladder Cancer AJCC v8
0.010 AlteredExpression disease BEFREE Stomatin-like protein-2 (SLP-2) gene belongs to the stomatin supergene family, and previous studies have revealed up-regulated SLP-2 expression in gallbladder cancer, lung cancer, and esophageal cancer, while the role of SLP-2 in colorectal cancer (CRC) remains unclear and needs further investigation. 30389319 2019
Stage III Gallbladder Cancer AJCC v8
0.010 AlteredExpression disease BEFREE Stomatin-like protein-2 (SLP-2) gene belongs to the stomatin supergene family, and previous studies have revealed up-regulated SLP-2 expression in gallbladder cancer, lung cancer, and esophageal cancer, while the role of SLP-2 in colorectal cancer (CRC) remains unclear and needs further investigation. 30389319 2019
CUI: C4525305
Disease: Stage IV Gallbladder Cancer AJCC v8
Stage IV Gallbladder Cancer AJCC v8
0.010 AlteredExpression disease BEFREE Stomatin-like protein-2 (SLP-2) gene belongs to the stomatin supergene family, and previous studies have revealed up-regulated SLP-2 expression in gallbladder cancer, lung cancer, and esophageal cancer, while the role of SLP-2 in colorectal cancer (CRC) remains unclear and needs further investigation. 30389319 2019
CUI: C1861453
Disease: Pseudohyperkalemia Cardiff
Pseudohyperkalemia Cardiff
0.030 GeneticVariation disease BEFREE The cryohydrocytosis phenotype, including South-east Asian Ovalocytosis, results from mutations in <i>SLC4A1</i>, and the very rare condition, stomatin-deficient cryohydrocytosis, is caused by mutations in <i>SLC2A1</i>. 29713289 2018
CUI: C0029456
Disease: Osteoporosis
Osteoporosis
0.010 Biomarker disease BEFREE Moreover, in stomatin transgenic mice, increased cell fusion leading to enhanced bone resorption and subsequent osteoporosis were observed. 27663861 2017
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms
0.030 Biomarker group BEFREE Stomatin-like protein 2 (SLP-2), a member of the stomatin protein family, has emerged as a potential molecular hallmark of tumor progression in several human malignancies. 26750533 2016
CUI: C0178874
Disease: Tumor Progression
Tumor Progression
0.020 Biomarker phenotype BEFREE Stomatin-like protein 2 (SLP-2), a member of the stomatin protein family, has emerged as a potential molecular hallmark of tumor progression in several human malignancies. 26750533 2016
CUI: C0178874
Disease: Tumor Progression
Tumor Progression
0.020 Biomarker phenotype BEFREE miRNA-1207-5p is associated with cancer progression by targeting stomatin-like protein 2 in esophageal carcinoma. 25695396 2015
CUI: C0007847
Disease: Malignant tumor of cervix
Malignant tumor of cervix
0.010 Biomarker disease BEFREE To investigate the prognostic role of stomatin-like protein 2 (STOML2) in cervical cancer. 25973071 2015
CUI: C0152018
Disease: Esophageal carcinoma
Esophageal carcinoma
0.010 Biomarker disease BEFREE miRNA-1207-5p is associated with cancer progression by targeting stomatin-like protein 2 in esophageal carcinoma. 25695396 2015
CUI: C0302592
Disease: Cervix carcinoma
Cervix carcinoma
0.010 Biomarker disease BEFREE To investigate the prognostic role of stomatin-like protein 2 (STOML2) in cervical cancer. 25973071 2015
CUI: C4048328
Disease: cervical cancer
cervical cancer
0.010 Biomarker disease BEFREE To investigate the prognostic role of stomatin-like protein 2 (STOML2) in cervical cancer. 25973071 2015
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms
0.030 AlteredExpression group BEFREE Several studies have indicated that overexpression of stomatin-like protein 2 (SLP-2) has been identified in several types of cancer. 23918306 2014
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.020 Biomarker group BEFREE Stomatin-like protein 2 (SLP-2) is a novel member of the stomatin superfamily and is found in several types of human tumors. 24190591 2014
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.020 AlteredExpression group BEFREE Several studies have indicated that overexpression of stomatin-like protein 2 (SLP-2) has been identified in several types of cancer. 23918306 2014
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma
0.010 AlteredExpression disease BEFREE Our data demonstrate for the first time that expression of stomatin, a poorly studied microdomain-forming protein, significantly changes in human tumors, thus pointing to its importance in the progression of NSCLC. 24533441 2014
CUI: C0079588
Disease: Ichthyosis, X-Linked
Ichthyosis, X-Linked
0.010 Biomarker disease BEFREE At the present time, there is a lack of data about the involvement of flotillins and stomatin in the development of non-small cell lung cancer (NSCLC) and soft tissue sarcomas (STS). 24533441 2014
CUI: C0278701
Disease: Gastric Adenocarcinoma
Gastric Adenocarcinoma
0.010 AlteredExpression disease BEFREE Increased expression of stomatin-like protein 2 (STOML2) predicts decreased survival in gastric adenocarcinoma: a retrospective study. 24258357 2014
Secondary malignant neoplasm of lymph node
0.010 AlteredExpression disease BEFREE Stomatin protein expression was down-regulated in 80% of NSCLC samples and this decrease significantly associated with presence of lymph node metastases. 24533441 2014
CUI: C1261473
Disease: Sarcoma
Sarcoma
0.010 Biomarker group BEFREE At the present time, there is a lack of data about the involvement of flotillins and stomatin in the development of non-small cell lung cancer (NSCLC) and soft tissue sarcomas (STS). 24533441 2014